Friday, 9 October 2009

Chimpanzees and HIV/AIDS Research


A large population of HIV-infected chimpanzees exists in the U.S. today due to their prior proposed use in HIV/AIDS experiments. An exact number is difficult to determine. According to a 1997 report prepared by NIH, “Although HIV infection of chimpanzees has not been an ideal model of disease, at least 198 chimpanzees have been used to date in HIV-related studies.” (7)

Eleven years after the launch of the chimpanzee breeding program to produce chimpanzees for AIDS research, NIH formally acknowledged the chimpanzee model of AIDS had been of limited success. In his testimony in 2000 before Congress, John Strandberg of NIH said:

Chimpanzees are the only animal, other than man, that can be infected with human immunodeficiency virus (HIV). For this reason, it was hoped that they could provide information on the progression from HIV infection to AIDS and in the development of treatments and vaccines. However, despite the fact that chimpanzees become persistently infected with HIV, we found that the development of clinical AIDS occurs in chimpanzees late or not at all. (8)

hiv / aids infection


It is not possible to become infected with HIV through sharing crockery and cutlery, insect/animal bites, touching, hugging or shaking hands, eating food prepared by someone with HIV, or toilet seats.

Unfortunately, around the world there are a number of myths and wrong beliefs about HIV/AIDS. Some people are for instance of the belief that only gay men or black people become infected with HIV, or that once infected, sex with a virgin is the cure. Such false notions do not benefit the fight against the disease. Here knowledge and information sharing becomes key. AIDS is best prevented by halting the spread of HIV, and a global as well as local effort is required.

Saturday, 19 September 2009

Outreach


Epidemiologist Roger Detels and four doctors from Southeast Asia discuss the status of the disease and control programs in key countries of the region.
By Leslie Evans
[HIV and AIDS remain at critical epidemic levels in some of the world's most populous countries, five specialists told a UCLA audience. But despite a general inability to supply patients with the kinds of drugs generally available in the United States, infection rates are going down rather than up in three of the four countries discussed. All four of the countries in the discussion below use HIV sentinel surveillance, periodic spot checking of a fixed size sample of selected risk groups in the population.
[UCLA epidemiologist Roger Detels and four of his graduate students, all doctors in their own right with experience in the HIV/AIDS control programs in their home countries, addressed a well-attended colloquium sponsored by the Center for Southeast Asian Studies in Bunche Hall April 23. The presenters, in addition to Dr. Detels, were Dr. Aye Myat Soe of Myanmar, Dr. Nhu To Nguyen of Vietnam, Dr. Chhorvann Chhea of Cambodia, and Dr. Warunee Punpanich of Thailand.

AIDS and PLANETARY HEALING


As we progress into this time period you call "The Transformation" or the "End Times," it seems very appropriate now for us to share with you a new level of seeing---a gradual realignment of viewpoint which will become a conduit from the focused, narrowly defined "Reality Box" you chose for yourselves when you entered the Earth Plane of existence.
In a very real way, the shift from what you call "Three Dimensional Thinking" to what is called "Multidimensional Thinking" IS that Transformation. In your Biblical literature, this change is described as occurring "in a moment, in the twinkling of an eye." My Dear Friends, the "twinkling" being referred to there is the SHIFT that occurs when your perspective of who and what you are changes from the fragmented, lonely minute being you once thought you were to a clear comprehension of your true Self and your relation to all existence Everywhere. And the only change that occurs is one of VIEWPOINT.

Sunday, 23 August 2009

Columbia celebrates World AIDS Day


COLUMBIA — In some of the coldest weather so far this winter, dozens of Columbia community members participated in World AIDS Day, walking down College Avenue with fistfuls of helium-filled balloons Monday evening. Illuminated by blinking lights, the 235 red balloons represented the lives of the 235 North Central Missouri residents who have died of AIDS during the past 27 years.
As of 2007, there were 202 people living with HIV in Boone County; 11 cases were diagnosed in 2007 alone, according to the Missouri Department of Health and Senior Services.

Are AIDS, Chronic Fatigue The Same Thing?


I received a thought provoking email this morning from (name withheld), who was diagnosed with both CFIDS or Chronic Fatigue Immune Dysfunction Syndrome and HIV-Negative AIDS. While her case may be something extremely rare, it might also be more common than we believe. Indeed, Karen believes that there is a connection between her suffering and all those cases of AIDS sufferers who are HIV negative.

Predicting the Spread of AIDS


We use differential equations to predict the spread of diseases through a population. The growth of AIDS is an example that follows the curve of the logistic equation, derived from solving a differential equation. We will see how to solve differential equations later in this chapter.
The HIV Virus invades a white blood cell...Image source.
Populations usually grow in an exponential fashion at first:
However, populations do not continue to grow forever, because food, water and other resources get used up over time. Differential equations are used to predict populations of people, animals, bacteria and viruses that are being affected by external events.

Medical Encyclopedia: AIDS


Saturday, 15 August 2009

Why AIDS Is Worse in Africa



Photo by Getty Images
By Anthony RuthPublished: May 22, 2007
As an economics student at Harvard, Emily Oster couldn’t figure out why no one in her field was working on HIV/AIDS—particularly what’s causing the epidemic in Africa—so she took up the topic herself. Now a research fellow at the Becker Center on Chicago Price Theory, she’s gottenAfricans are four to five times more likely to contract HIV from unprotected intercourse with an HIV-positive person. Oster attributes this to higher instances of bacterial and viral STDs in Africans—nearly half carry the herpes virus—which make them more susceptible to HIV.
Finally, Oster used death rates to estimate the prevalence of AIDS in the general African population. She found that the popular UN estimates of African AIDS cases, which are based on tests of pregnant women at prenatal clinics, are about three times too high. However, Oster says, the news is not as good as it sounds. “My study, which estimated changes in the infection rate over time, also drew a second, chilling conclusion: In Africa, HIV is spreading as quickly as ever.”
In addition to the December Esquire article, Oster’s research on AIDS was featured in a January New York Times story on the future of economics.

HIV/AIDS and Tumours


HIV/AIDS and Tumours (2) Squamous Cell CarcinomaPhoto: Philippe Kestelyn
HIV/AIDS and the Eye Teaching Set 13/24

What Are HIV and AIDS?


HIV (human immunodeficiency virus) is the virus that causes AIDS (acquired immune deficiency syndrome). AIDS is a disease of the immune system that has treatment options, but no cure, at the present time. Most people just say “HIV/AIDS” when they are talking about either the virus (HIV) or the disease it causes (AIDS).
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HIV is a blood-borne virus. That means it can spread when the blood or bodily fluids of someone who’s infected comes in contact with the blood, broken skin, or mucous membranes of an uninfected person. Sharing needles or other equipment used for injection drug use and engaging in other risky behaviors are the two main ways that HIV is spread. Infected pregnant women also can pass HIV to their babies during pregnancy, delivery, and breastfeeding.
HIV destroys certain cells, called CD4+ cells, in the immune system—that’s the body’s disease fighting department. Without these cells, a person with HIV can’t fight off germs and diseases. In fact, loss of these cells in people with HIV is a key predictor of the development of AIDS. Because of their weakened immune system, people with AIDS often develop infections of the lungs, brain, eyes, and other organs, and many suffer dangerous weight loss, diarrhea, and a type of cancer called Kaposi's sarcoma. [1]
The good news is that HIV isn’t the death sentence it was when the epidemic began. This is thanks in large part to a treatment called HAART (highly active antiretroviral therapy). HAART is a combination of three or more antiretroviral medications that can hold back the virus and prevent or decrease symptoms of illness.
How Many People Have HIV/AIDS?
HIV/AIDS has been a global epidemic for more than 25 years; today's youth have never known a world without it. In the United States, the estimates indicate that more than 1 million people are living with HIV or AIDS. [2]
In 2007, 37,041 new AIDS disease cases were reported. Recently, the Centers for Disease Control and Prevention (CDC) published HIV incidence estimates using new methods. They found that in 2006, an estimated 56,300 new HIV infections occurred—a number that is much higher than the previous estimate of 40,000 new infections annually. This means that more people are infected with HIV than we originally thought. [2]
CDC estimates that close to one-quarter of the people in the United States who are infected with HIV do not know they are infected. [2]
Can You Tell if Someone Is Infected With HIV or Has AIDS?
You cannot tell by looking at them if someone is infected with HIV. A person can be infected with HIV for many years, and the virus may or may not progress to the disease of AIDS. A medical test is the only way to know if a person has HIV or has developed AIDS. [1]
How Are Drug Abuse and HIV Related?
Drug abuse and addiction have been closely linked with HIV/AIDS since the beginning of the epidemic. Although injection drug use is well known in this regard, the role that non-injection drug abuse plays more generally in the spread of HIV is less recognized.
Injection drug use. People typically associate drug abuse and HIV/AIDS with injection drug use and needle sharing. Injection drug use refers to when a drug is injected into a tissue or vein with a needle. When injection drug users share “equipment”—such as needles, syringes, and other drug injection paraphernalia—HIV can be transmitted between users. Other infections—such as hepatitis C—can also be spread this way. Hepatitis C can cause liver disease and permanent liver damage.
Poor judgment and risky behavior. Drug abuse by any method (not just injection) can put a person at risk for contracting HIV. Drug and alcohol intoxication affect the way a person makes decisions and can lead to unsafe sexual practices, which puts them at risk for getting HIV or transmitting it to someone else.
Biological effects of drugs. Drug abuse and addiction can affect a person's overall health, making them more susceptible to HIV or, in people with HIV, worsen the progression of HIV and its consequences, especially in the brain. For example, research has shown that HIV causes more harm to nerve cells in the brain and greater cognitive damage among methamphetamine abusers than among people with HIV who do not abuse drugs. In animal studies, methamphetamine has been shown to increase the amount of HIV in brain cells.
Drug abuse treatment. Since the late 1980s, researchers found that if you treat drug abuse you can prevent the spread of HIV. Drug abusers in treatment stop or reduce their drug use and related risk behaviors, including drug injection and unsafe sexual practices. Drug treatment programs also serve an important role in getting out good information on HIV/AIDS and related diseases, providing counseling and testing services, and offering referrals for medical and social services. [3]
How Are Teens Affected?
Young people are at risk for contracting HIV and developing AIDS. According to CDC, about 35,845 young people age 13 to 24 in the United States had been diagnosed with AIDS by the end of 2007. In the past, most of those cases were in adolescent males. That ratio is changing as more females become infected. [4]
In youth, as in adults, some populations are disproportionately affected. That means that some populations are more affected than others. For example, Blacks/African Americans age 13 to 19 represent only 17% of the U.S. teenage population, but accounted for 72% of new AIDS cases in 2007. [4] The reasons for this gap aren’t completely understood; in fact, Black/African American youth have lower rates of drug abuse than Whites and Hispanics. This remains a strong research priority for NIDA. [4]
In general, middle and late adolescence is a time when young people engage in risk-taking and sensation-seeking behaviors that may put them in jeopardy of contracting HIV. Regardless of whether a young person takes drugs, unsafe sexual practices increase a person's risk of contracting HIV. But drugs and alcohol can increase the chances of unsafe behavior by altering judgment and decision making.
How Can Teens Protect Themselves?
The best way to protect yourself is to stay healthy and think clearly. Choose not to use drugs. Know that drug use can change the brain and affect the way people make decisions and weigh risks.
Why Is NIDA Studying HIV and AIDS?
Since the HIV/AIDS epidemic began, injection drug use has directly and indirectly accounted for about one-third of the AIDS cases in the United States. We now know that the poor judgment and impaired critical thinking that can result from non-injection drug abuse also can contribute in a big way to the spread of this lethal virus through risky behavior. [5]
What Can I Do to Help?
Go to http://hiv.drugabuse.gov/index.html for more information on learning the link between drug abuse and HIV/AIDS. On World AIDS Day—every December 1st—participate by spreading the word that drug abuse and HIV/AIDS can shorten lives. Tell your friends what you've learned and how they can avoid infection.

References
1.
Centers for Disease Control and Prevention, National Center for HIV, STD, and TB Prevention. What Is HIV? (http://www.cdc.gov/hiv/pubs/faq/faq1.htm):Atlanta, GA: CDC, DHHS. Revised October 2006. Retrieved June 2009.
2.
Centers for Disease Control and Prevention, National Center for HIV, STD, and TB Prevention. Basic Statistics AIDS Cases by Exposure Category (http://www.cdc.gov/hiv/stats.htm#exposure):Atlanta, GA: CDC, DHHS. Revised February 2009. Retrieved June 2009.
3.
National Institute on Drug Abuse. Research Report Series on HIV/AIDS(http://www.nida.nih.gov/ResearchReports/hiv/hiv.html):Bethesda, MD: NIDA, NIH, DHHS. Revised 2006. Retrieved June 2009.
4.
Centers for Disease Control and Prevention. HIV/AIDS Surveillance in Adolescents, L265 Slide Series (http://www.cdc.gov/hiv/topics/surveillance/resources/slides/adolescents/slides/Adolescents.pdf, PDF, 902 KB):Atlanta, GA: CDC, DHHS. Revised May 2009. Retrieved June 2009.
5.
World AIDS Day. World AIDS Day (http://www.worldaidsday.org/):Retrieved June 2009.[Back to top]

Thursday, 13 August 2009

What is AIDS?

AIDS stands for: Acquired Immune Deficiency Syndrome
AIDS is a medical condition. A person is diagnosed with AIDS when their immune system is too weak to fight off infections.
Since AIDS was first identified in the early 1980s, an unprecedented number of people have been affected by the global AIDS epidemic. Today, there are an estimated 33 million people living with HIV/AIDS.

HIV/AIDS: Central America, South America, & Caribbean


The AIDS crisis in Latin America takes many forms that vary from country to country. Governments and civil society have responded accordingly, some more effectively than others. While the region claims some of the world’s more daring strategies for treating AIDS and slowing its spread, AIDS advocates in the region also must contend with a culture of machismo that hinders vital public education efforts.
Nearly 140,000 Latin Americans were diagnosed with HIV in 2N005. About 1.6 million people are now believed to be living with the virus there. Throughout most of the region, the primary form of transmission is between men who have sex with men, although the disease has spread into the homosexual population as well.
Brazil and Cuba, despite their poor infrastructures and impoverished populations, have stabilized the spread of HIV and AIDS in their countries through health care programs that allow HIV-positive citizens to obtain treatment without calling attention to their status. The programs have significantly curbed those nations’ AIDS death rates and have even stabilized the disease’s spread. However, in order to protect new generations from falling victim to the epidemic, Brazil and Cuba must also reverse the stigma that forces many HIV and AIDS patients to hide their disease.

Wednesday, 12 August 2009

News results for hiv aids




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AIDS - Wikipedia, the free encyclopedia
Although treatments for AIDS and HIV can slow the course of the

Cause

For more details on tPulmonary infectionshis topic, see HIV.

Scanning electron micrograph of HIV-1, colored green, budding from a cultured lymphocyte.
AIDS is the most severe acceleration of infection with HIV. HIV is a retrovirus that primarily infects vital organs of the human immune system such as CD4+ T cells (a subset of T cells), macrophages and dendritic cells. It directly and indirectly destroys CD4+ T cells.[34]
Once HIV has killed so many CD4+ T cells that there are fewer than 200 of these cells per microliter (µL) of blood, cellular immunity is lost. Acute HIV infection progresses over time to clinical latent HIV infection and then to early symptomatic HIV infection and later to AIDS, which is identified either on the basis of the amount of CD4+ T cells remaining in the blood, and/or the presence of certain infections, as noted above.[35]
In the absence of antiretroviral therapy, the median time of progression from HIV infection to AIDS is nine to ten years, and the median survival time after developing AIDS is only 9.2 months.[36] However, the rate of clinical disease progression varies widely between individuals, from two weeks up to 20 years.
Many factors affect the rate of progression. These include factors that influence the body's ability to defend against HIV such as the infected person's general immune function.[37][38] Older people have weaker immune systems, and therefore have a greater risk of rapid disease progression than younger people.
Poor access to health care and the existence of coexisting infections such as tuberculosis also may predispose people to faster disease progression.[36][39][40] The infected person's genetic inheritance plays an important role and some people are resistant to certain strains of HIV. An example of this is people with the homozygous CCR5-Δ32 variation are resistant to infection with certain strains of HIV.[41] HIV is genetically variable and exists as different strains, which cause different rates of clinical disease progression.[42][43][44]

Sexual transmission
Sexual transmission occurs with the contact between sexual secretions of one person with the rectal, genital or oral mucous membranes of another. Unprotected receptive sexual acts are riskier than unprotected insertive sexual acts, and the risk for transmitting HIV through unprotected anal intercourse is greater than the risk from vaginal intercourse or oral sex.
However, oral sex is not entirely safe, as HIV can be transmitted through both insertive and receptive oral sex.[45][46] Sexual assault greatly increases the risk of HIV transmission as condoms are rarely employed and physical trauma to the vagina or rectum occurs frequently, facilitating the transmission of HIV.[47]
Other sexually transmitted infections (STI) increase the risk of HIV transmission and infection, because they cause the disruption of the normal epithelial barrier by genital ulceration and/or microulceration; and by accumulation of pools of HIV-susceptible or HIV-infected cells (lymphocytes and macrophages) in semen and vaginal secretions. Epidemiological studies from sub-Saharan Africa, Europe and North America suggest that genital ulcers, such as those caused by syphilis and/or chancroid, increase the risk of becoming infected with HIV by about fourfold. There is also a significant although lesser increase in risk from STIs such as gonorrhea, chlamydia and trichomoniasis, which all cause local accumulations of lymphocytes and macrophages.[48]
Transmission of HIV depends on the infectiousness of the index case and the susceptibility of the uninfected partner. Infectivity seems to vary during the course of illness and is not constant between individuals. An undetectable plasma viral load does not necessarily indicate a low viral load in the seminal liquid or genital secretions.
However, each 10-fold increase in the level of HIV in the blood is associated with an 81% increased rate of HIV transmission.[48][49] Women are more susceptible to HIV-1 infection due to hormonal changes, vaginal microbial ecology and physiology, and a higher prevalence of sexually transmitted diseases.[50][51]
People who have been infected with one strain of HIV can still be infected later on in their lives by other, more virulent strains.
Infection is unlikely in a single encounter. High rates of infection have been linked to a pattern of overlapping long-term sexual relationships. This allows the virus to quickly spread to multiple partners who in turn infect their partners. A pattern of serial monogamy or occasional casual encounters is associated with lower rates of infection.[52]
HIV spreads readily through heterosexual sex in Africa, but less so elsewhere. One possibility being researched is that schistosomiasis, which affects up to 50 per cent of women in parts of Africa, damages the lining of the vagina.[53][54]

Exposure to blood-borne pathogens

Cause


For more details on tPulmonary infectionshis topic, see HIV.

Scanning electron micrograph of HIV-1, colored green, budding from a cultured lymphocyte.
AIDS is the most severe acceleration of infection with HIV. HIV is a retrovirus that primarily infects vital organs of the human immune system such as CD4+ T cells (a subset of T cells), macrophages and dendritic cells. It directly and indirectly destroys CD4+ T cells.[34]
Once HIV has killed so many CD4+ T cells that there are fewer than 200 of these cells per microliter (µL) of blood, cellular immunity is lost. Acute HIV infection progresses over time to clinical latent HIV infection and then to early symptomatic HIV infection and later to AIDS, which is identified either on the basis of the amount of CD4+ T cells remaining in the blood, and/or the presence of certain infections, as noted above.[35]
In the absence of antiretroviral therapy, the median time of progression from HIV infection to AIDS is nine to ten years, and the median survival time after developing AIDS is only 9.2 months.[36] However, the rate of clinical disease progression varies widely between individuals, from two weeks up to 20 years.
Many factors affect the rate of progression. These include factors that influence the body's ability to defend against HIV such as the infected person's general immune function.[37][38] Older people have weaker immune systems, and therefore have a greater risk of rapid disease progression than younger people.
Poor access to health care and the existence of coexisting infections such as tuberculosis also may predispose people to faster disease progression.[36][39][40] The infected person's genetic inheritance plays an important role and some people are resistant to certain strains of HIV. An example of this is people with the homozygous CCR5-Δ32 variation are resistant to infection with certain strains of HIV.[41] HIV is genetically variable and exists as different strains, which cause different rates of clinical disease progression.[42][43][44]

Sexual transmission
Sexual transmission occurs with the contact between sexual secretions of one person with the rectal, genital or oral mucous membranes of another. Unprotected receptive sexual acts are riskier than unprotected insertive sexual acts, and the risk for transmitting HIV through unprotected anal intercourse is greater than the risk from vaginal intercourse or oral sex.
However, oral sex is not entirely safe, as HIV can be transmitted through both insertive and receptive oral sex.[45][46] Sexual assault greatly increases the risk of HIV transmission as condoms are rarely employed and physical trauma to the vagina or rectum occurs frequently, facilitating the transmission of HIV.[47]
Other sexually transmitted infections (STI) increase the risk of HIV transmission and infection, because they cause the disruption of the normal epithelial barrier by genital ulceration and/or microulceration; and by accumulation of pools of HIV-susceptible or HIV-infected cells (lymphocytes and macrophages) in semen and vaginal secretions. Epidemiological studies from sub-Saharan Africa, Europe and North America suggest that genital ulcers, such as those caused by syphilis and/or chancroid, increase the risk of becoming infected with HIV by about fourfold. There is also a significant although lesser increase in risk from STIs such as gonorrhea, chlamydia and trichomoniasis, which all cause local accumulations of lymphocytes and macrophages.[48]
Transmission of HIV depends on the infectiousness of the index case and the susceptibility of the uninfected partner. Infectivity seems to vary during the course of illness and is not constant between individuals. An undetectable plasma viral load does not necessarily indicate a low viral load in the seminal liquid or genital secretions.
However, each 10-fold increase in the level of HIV in the blood is associated with an 81% increased rate of HIV transmission.[48][49] Women are more susceptible to HIV-1 infection due to hormonal changes, vaginal microbial ecology and physiology, and a higher prevalence of sexually transmitted diseases.[50][51]
People who have been infected with one strain of HIV can still be infected later on in their lives by other, more virulent strains.
Infection is unlikely in a single encounter. High rates of infection have been linked to a pattern of overlapping long-term sexual relationships. This allows the virus to quickly spread to multiple partners who in turn infect their partners. A pattern of serial monogamy or occasional casual encounters is associated with lower rates of infection.[52]
HIV spreads readily through heterosexual sex in Africa, but less so elsewhere. One possibility being researched is that schistosomiasis, which affects up to 50 per cent of women in parts of Africa, damages the lining of the vagina.[53][54]

Exposure to blood-borne pathogens

Protesters seek cheaper drugs at HIV/AIDS meeting


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Papua better protecting women against HIV/AIDS






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Tuesday, 11 August 2009

skip to main | skip to sidebar HIV AIDS




History

Main article: Origin of AIDSAIDS was first reported June 5, 1981, when the U.S. Centers for Disease Control (CDC) recorded a cluster of Pneumocystis carinii pneumonia (now still classified as PCP but known to be caused by Pneumocystis jirovecii) in five homosexual men in Los Angeles.[138] In the beginning, the CDC did not have an official name for the disease, often referring to it by way of the diseases that were associated with it, for example, lymphadenopathy, the disease after which the discoverers of HIV originally named the virus.[70][71] They also used Kaposi's Sarcoma and Opportunistic Infections, the name by which a task force had been set up in 1981.[139] In the general press, the term GRID, which stood for Gay-related immune deficiency, had been coined.[140] The CDC, in search of a name, and looking at the infected communities coined “the 4H disease,” as it seemed to single out Haitians, homosexuals, hemophiliacs, and heroin users.[141] However, after determining that AIDS was not isolated to the homosexual community,[139] the term GRID became misleading and AIDS was introduced at a meeting in July 1982.[142] By September 1982 the CDC started using the name AIDS, and properly defined the illness.[143]A more controversial theory known as the OPV AIDS hypothesis suggests that the AIDS epidemic was inadvertently started in the late 1950s in the Belgian Congo by Hilary Koprowski's research into a poliomyelitis vaccine.[144][145] According to scientific consensus, this scenario is not supported by the available evidence.[146][147][148]A recent study states that HIV probably moved from Africa to Haiti and then entered the United States around 1969.[149
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TB ravages HIV/Aids patients: WHO
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Hepatitis C

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Main article: Origin of AIDSAIDS was first reported June 5, 1981, when the U.S. Centers for Disease Control (CDC) recorded a cluster of Pneumocystis carinii pneumonia (now still classified as PCP but known to be caused by Pneumocystis jirovecii) in five homosexual men in Los Angeles.[138] In the beginning, the CDC did not have an official name for the disease, often referring to it by way of the diseases that were associated with it, for example, lymphadenopathy, the disease after which the discoverers of HIV originally named the virus.[70][71] They also used Kaposi's Sarcoma and Opportunistic Infections, the name by which a task force had been set up in 1981.[139] In the general press, the term GRID, which stood for Gay-related immune deficiency, had been coined.[140] The CDC, in search of a name, and looking at the infected communities coined “the 4H disease,” as it seemed to single out Haitians, homosexuals, hemophiliacs, and heroin users.[141] However, after determining that AIDS was not isolated to the homosexual community,[139] the term GRID became misleading and AIDS was introduced at a meeting in July 1982.[142] By September 1982 the CDC started using the name AIDS, and properly defined the illness.[143]A more controversial theory known as the OPV AIDS hypothesis suggests that the AIDS epidemic was inadvertently started in the late 1950s in the Belgian Congo by Hilary Koprowski's research into a poliomyelitis vaccine.[144][145] According to scientific consensus, this scenario is not supported by the available evidence.[146][147][148]A recent study states that HIV probably moved from Africa to Haiti and then entered the United States around 1969.[149
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TB ravages HIV/Aids patients: WHO
Pulmonary infections
Tumors and malignancies
History
Can AIDS be treated?
hiv aids India and China
AIDS Lifecycle Includes Protest in Closing Ceremon...
Hepatitis A
Hepatitis B
How hepatitis C is spread
Hepatitis C

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ismail View my complete profile

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Patients with HIV infection have substantially increased incidence of several cancers. This is primarily due to co-infection with an oncogenic DNA virus, especially Epstein-Barr virus (EBV), Kaposi's sarcoma-associated herpesvirus (KSHV), and human papillomavirus (HPV).[27][28]Kaposi's sarcoma (KS) is the most common tumor in HIV-infected patients. The appearance of this tumor in young homosexual men in 1981 was one of the first signals of the AIDS epidemic. Caused by a gammaherpes virus called Kaposi's sarcoma-associated herpes virus (KSHV), it often appears as purplish nodules on the skin, but can affect other organs, especially the mouth, gastrointestinal tract, and lungs.High-grade B cell lymphomas such as Burkitt's lymphoma, Burkitt's-like lymphoma, diffuse large B-cell lymphoma (DLBCL), and primary central nervous system lymphoma present more often in HIV-infected patients. These particular cancers often foreshadow a poor prognosis. In some cases these lymphomas are AIDS-defining. Epstein-Barr virus (EBV) or KSHV cause many of these lymphomas.Cervical cancer in HIV-infected women is considered AIDS-defining. It is caused by human papillomavirus (HPV).[29]In addition to the AIDS-defining tumors listed above, HIV-infected patients are at increased risk of certain other tumors, notably Hodgkin's disease and anal and rectal carcinomas. Malignancies that affect AIDS patients such as Kaposi's sarcoma and AIDS-related Non-Hodgkin lymphoma often arise in the gastrointestinal tract. [30]However, the incidence of many common tumors, such as breast cancer or colon cancer, does not increase in HIV-infected patients. In areas where HAART is extensively used to treat AIDS, the incidence of many AIDS-related malignancies has decreased, but at the same time malignant cancers overall have become the most common cause of death of HIV-infected patients.[31]
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Pneumocystis pneumonia (originally known as Pneumocystis carinii pneumonia, and still abbreviated as PCP, which now stands for Pneumocystis pneumonia) is relatively rare in healthy, immunocompetent people, but common among HIV-infected individuals. It is caused by Pneumocystis jirovecii.Before the advent of effective diagnosis, treatment and routine prophylaxis in Western countries, it was a common immediate cause of death. In developing countries, it is still one of the first indications of AIDS in untested individuals, although it does not generally occur unless the CD4 count is less than 200 cells per µL of blood.[16]Tuberculosis (TB) is unique among infections associated with HIV because it is transmissible to immunocompetent people via the respiratory route, is easily treatable once identified, may occur in early-stage HIV disease, and is preventable with drug therapy. However, multidrug resistance is a potentially serious problem.Even though its incidence has declined because of the use of directly observed therapy and other improved practices in Western countries, this is not the case in developing countries where HIV is most prevalent. In early-stage HIV infection (CD4 count >300 cells per µL), TB typically presents as a pulmonary disease. In advanced HIV infection, TB often presents atypically with extrapulmonary (systemic) disease a common feature. Symptoms are usually constitutional and are not localized to one particular site, often affecting bone marrow, bone, urinary and gastrointestinal tracts, liver, regional lymph nodes, and the central nervous system.[17]
Posted by ismail at 01:14

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EPIDEMIC ERUPTSContaminated water blamed for gastro in Landhi GENEVA: The World Health Organisation warned on Tuesday that progress in tackling tuberculosis was far too slow, as it doubled its estimate of the ravages the disease is causing among HIV/Aids patients.Some 9.27 million people contracted TB in 2007, an increase of about 30,000 over the previous year mainly in line with population growth, according to the WHO’s annual report on tuberculosis control.They included some 1.4 million people with HIV/Aids, compared to an estimated 600,000 in 2006 reported last year.More than one death in four — 456,000 of the 1.75 million tuberculosis deaths recorded in 2007 — is now thought to involve an HIV/Aids patient.‘These findings point to an urgent need to find, prevent and treat tuberculosis in people living with HIV and to test for HIV in all patients with TB in order to provide prevention, treatment and care,’ said WHO Director General Margaret Chan in a statement.However, the report reiterated that there were severe shortcomings in tackling tuberculosis and coordinated care for both diseases largely due to feeble heath care in the developing countries that are the hardest hit.Just one in seven HIV patients get vital preventive treatment for TB, said WHO HIV/Aids director Kevin De Cock.Overall, more than one third of tuberculosis cases are not diagnosed, leaving many out of reach of treatment and, crucially, increasing the risk of spreading the contagious disease, according to the UN health agency.While the overall rate of TB infection fell in three years to 139 cases per 100,000 people, the improvement was too slow, said Mario Raviglione, the agency’s anti-tuberculosis chief.’We are talking about less than one per cent per year, which will get us to potentially eliminate TB in a very distant future: we are talking centuries if not millenia in a way,’ he told journalists. The growth in the estimated impact on HIV/Aids patients was largely down to better data and understanding.’The revision is illustrative of the fact that people living with HIV have a risk of developing tuberculosis that’s 20 times greater than HIV negative people,’ said De Cock.Despite progress in testing TB patients for HIV in Africa, the combination of poor diagnosis, rising drug resistance and the evidence of the impact on highly vulnerable HIV/Aids patients have heightened alarm among health experts.Detection of the highly contagious disease has stagnated after a sharp improvement nine years ago, while the impact drug resistant strains of the TB bacteria has grown to infect an estimated 500,000 people.Just one per cent of them receive treatment and 150,000 of them die, according to the WHO, which regards resistance as the ‘achilles heel’ of the anti-TB drive.‘The scale-up of interventions to deal with multidrug TB is not at the pace we would like to see and is far from the targets that have been established,’ Raviglione said.Furthermore, 10 per cent of them were almost incurable extra-resistant strains (XDR-TB) that are now found in 55 countries.The WHO is gathering the 27 countries that account for 85 per cent of multidrug resistant cases of tuberculosis — including India, China, Russia, South Africa and Bangladesh - for a meeting in Beijing on April 1.‘You could be in middle of a drug resistant TB epidemic and not even know about it,’ De Cock pointed out.
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